Table 2 Special gene sets
From: Mining SOM expression portraits: feature selection and integrating concepts of molecular function
| Â | Gene seta | Selection criterion | # of genes | Top three overrepresented GO-setsb |
|---|---|---|---|---|
a | Highly expressed | Top ranked expression in the global overexpression list | 2,227 (10%) | Cation homeostasis, chemical homeostasis, multicellular organism development |
b | Highly ranked | Top ranked in the global rank product list c | 2,227 (10%) | Anatomical structure morphogenesis, axiogenesis, cell migration |
c | Inactive (consistently not or weakly expressed) | Member of the N-range of the hook curve, absent in all tissues | 688 | Receptor activity, signal transduction, plasma membrane |
d |  | Present call parameter pc = 0 in all tissues | 1,156 | Receptor-protein signaling pathway, neurological system process, signal transduction |
e | Housekeepers (consistently expressed) | Not member of the N-range of the hook curve, present in all tissues | 3,561 | Anti-apoptosis, apoptosis, cell development, RNA processing, DNA/RNA binding, DNA metabolic process, metabolic process, transcription, translation d… . |
f |  | Present call parameter pc = 1 in all tissues | 3,167 | see e |
g | Â | Top ranked in mean expression list averaged over all tissues | 2,227 (10%) | Macromolecular complex assembly, nucleic acid metabolic process, regulation of cellular metabolic process |
h | Â | Taken from ref. [31], criterion analogous to g | 852 | Cellular macromolecule metabolic process, cellular protein metabolic process, protein metabolic process |